# Genetics

## What is ChROseq and how does it work

At the moment of writing this post, I’m sitting on the plane flying to Cornell. There I will learn a beautiful technique called Chromatin Run-On and Sequencing, or ChRO-seq. Thirteen hours of travel is getting to the point of breaking my soul – I have finished most of work I can comfortablely do with one screen on a samll laptop. So I decided to write down what I know so far about ChRO-seq in preparation for my upcoming training tomorrow.

## Haplotype, LD, and Association Tests

Table of content Table of content What Are Haplotype and Linkage Disequilibrium (LD) Quantify LD Linkage Disequilibrium Coefficient ($D$): Standardized Linkage Disequilibrium Coefficient ($D’$) Correlation coefficient ($\gamma^2$) Now why do we care about LD and haplotype? LD is an indication of deviation from Hardy-Weinberg equilibrium. This is the first post of my QE prep series. I’ll be taking notes on my study for general knowledge section of my QE.